L0669

Monoclonal Anti-Leukemia Inhibitory Factor antibody produced in mouse

clone 9824, purified immunoglobulin, lyophilized powder

• 동의어(들): Anti-CDF, Anti-Cholinergic differentiation factor, Anti-HILDA, Anti-LIF
• UNSPSC 코드: 51111800
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 9824, monoclonal
• 양식: lyophilized powder
• 종 반응성: human
• 기술: capture ELISA: 2-4 μg/mL; immunohistochemistry: 25 μg/mL; neutralization: suitable; western blot: 1-2 μg/mL
• UniProt 수납 번호: P15018
• 저장 온도: −20°C
• 유전자 정보: human ... LIF(3976)

설명

면역원

purified, E. coli-derived recombinant human leukemia inhibitory factor.

생화학적/생리학적 작용

Leukemia inhibitory factor (LIF) is a pleotrophic glycoprotein that belongs to the IL-6 family of cytokines. It is secreted by many cell types such as, fibroblasts, macrophages, T cells, monocytes, liver cells, osteoblasts and cells of endometrium. A variety of signal transduction pathways are triggered in response to LIF including ERK/MAPK, JAK1, PI3K, STAT3, Jun-c Fos and NF-κB. The various functions of LIF include proliferation of adult human T cells, maintenance of pluripotency of embryonic stem cells and inhibition of leukemic cell differentiation.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)