M6518

Macrophage Colony-Stimulating Factor human

≥98% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• 동의어(들): MCSF
• MDL number: MFCD00166591
• UNSPSC 코드: 12352202
• NACRES: NA.77

속성

• Product Name: Macrophage Colony-Stimulating Factor human, M-CSF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
• 생물학적 소스: human
• Quality Level: 200
• 재조합: expressed in E. coli
• 분석: ≥98% (SDS-PAGE and HPLC)
• 양식: lyophilized powder
• 효능: 0.500-5.000 ng/mL ED₅₀
• 품질: endotoxin tested
• 분자량: dimer 37 kDa
• 포장: pkg of 10 μg
• 기술: cell culture | mammalian: suitable
• 불순물: ≤1.000 EU/μg
• 색상: white
• UniProt 수납 번호: P09603
• 저장 온도: −20°C
• 유전자 정보: human ... CSF1(1435)

설명

일반 설명

Macrophage Colony-Stimulating Factor (M-CSF) is a hematopoietic growth factor, which modulates the proliferation, differentiation and functional activation of monocytes. It is produced by fibroblasts, endothelial cells and bone marrow stromal cells. MCSF stimulates the functions of mature monocytes and macrophages.

애플리케이션

Macrophage Colony-Stimulating Factor human has been used for the differentiation of bone marrow-derived macrophages (BMDMs) and human monocyte-derived macrophages (MDMs). It has also been used for cell culture.

생화학적/생리학적 작용

Macrophage colony-stimulating factor (M-CSF) augments many of the physiological functions of macrophages, and support osteoclast differentiation.

기타 정보

159 amino acids including N-terminal methionine (each monomer).

물리적 형태

Lyophilized from a sterile filtered buffered solution.

분석 메모

The proliferative activity is tested in culture using the cytokine-dependent murine monocytic cell line M-NFS-60 cells.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)