M7441

Monoamine Oxidase B human

recombinant, expressed in baculovirus infected BTI insect cells

• 동의어(들): MAO-B
• EC 번호: 1.4.3.4 (BRENDA, IUBMB)
• MDL number: MFCD04040933
• UNSPSC 코드: 12352204
• NACRES: NA.54

속성

• 재조합: expressed in baculovirus infected BTI insect cells
• Quality Level: 100
• 양식: liquid
• enzyme activity: ≥1 U/mg
• 포장: vial of ~2.5 mg
• UniProt 수납 번호: P27338
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human ... MAOB(4129)

설명

일반 설명

Monoamine Oxidase B is a mitochondrial outermembrane flavoenzyme that is a target for antidepressant and neuroprotective drugs.

애플리케이션

Drugs that inhibit monoamine oxidase B activity are used for the treatment of various neurological disorders including depression.

Monoamine Oxidase B has been used in a study to assess the effect of age in 23 different regions of the human brain. It has also been used in a study to determine the specific locations of monoamine oxidase in the human brain.

생화학적/생리학적 작용

MAO′s are proteins of the mitochondrial membrane. These enzymes are responsible for catalyzing oxidative deamination of endo- and xenobiotic amines. Substrate specificity differs for each isozyme.

단위 정의

kynuramine deamination activity: One unit will deaminate 1 nanomole of kynuramine per minute at pH 7.4 at 37 deg C.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)