M7566

Monoamine Oxidase Insect Cell Control

recombinant, expressed in wild-type baculovirus infected BTI insect cells

• 동의어(들): MAO negative control
• MDL number: MFCD08705570
• UNSPSC 코드: 12352204
• NACRES: NA.54

속성

• 재조합: expressed in wild-type baculovirus infected BTI insect cells
• Quality Level: 200
• 양식: liquid
• 포장: vial of ~2.5 mg
• 배송 상태: dry ice
• 저장 온도: −70°C

설명

일반 설명

Monoamine oxidase is a mitochondrial outermembrane flavoenzyme that is a target for antidepressant and neuroprotective drugs.

애플리케이션

Monoamine Oxidase inhibitors (MAOIs) are used to treat mental disorders including depression and Parkinson′s.

This product is suitable as a negative control for MAO-A and MAO-B.

생화학적/생리학적 작용

Monoamine Oxidase (MAO) is an integral flavoprotein of the outer mitochondrial membrane. MAOs are responsible for catalyzing the oxidative deamination of a wide variety of xenobiotic and endobiotic primary, secondary, and tertiary amines. The primary endogenous function of MAOs involves the inactivation of monoamine neurotransmitters, such as serotonin and dopamine. MAOs exist in two isoforms, MAO-A and MAO-B, which share approximately 70% sequence identity on the amino acid level.1 Both isoforms are nearly ubiquitous in mammals, but show particularly high enzymatic activity in the central nervous system and liver.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)