N1165

Pimonidazole

≥98% (HPLC)

• 동의어(들): NSC 380540, PD 126675;, Ro 03-8799;, alpha-((2-Nitroimidazol-1-yl)methyl)-1-piperidineethanol;, alpha-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol
• 실험식(Hill 표기법): C₁₁H₁₈N₄O₃
• CAS Number: 70132-50-2
• Molecular Weight: 254.29
• MDL number: MFCD00867974
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329818508
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: yellow
• solubility: DMSO: >20 mg/mL
• 저장 온도: 2-8°C
• SMILES string: OC(CN1CCCCC1)Cn2ccnc2[N+]([O-])=O
• InChI: 1S/C11H18N4O3/c16-10(8-13-5-2-1-3-6-13)9-14-7-4-12-11(14)15(17)18/h4,7,10,16H,1-3,5-6,8-9H2
• InChI key: WVWOOAYQYLJEFD-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Pimonidazole is an effective and nontoxic exogenous 2-nitroimidazole hypoxia marker.

Pimonidazole is an effective and nontoxic exogenous 2-nitroimidazole hypoxia marker. Pimonidazole forms adducts with thiol groups in proteins, peptides and amino acids.

Pimonidazole possesses a nitro group at position 2 and an imidazole ring. Pimonidazole undergoes reduction and is activated in hypoxic cells.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable