N7261

Nortriptyline hydrochloride

≥98% (HPLC), powder

• 동의어(들): 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine hydrochloride, Desmethylamitriptyline hydrochloride
• 실험식(Hill 표기법): C₁₉H₂₁N · HCl
• CAS Number: 894-71-3
• Molecular Weight: 299.84
• EC Number: 212-973-0
• MDL number: MFCD00058024
• UNSPSC 코드: 41116107
• PubChem Substance ID: 24278107
• NACRES: NA.77

속성

• Quality Level: 200
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to off-white
• solubility: ethanol: 100 mg/mL; H₂O: soluble
• 주관자: Eli Lilly
• SMILES string: Cl.CNCC\C=C1\c2ccccc2CCc3ccccc13
• InChI: 1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-11,20H,6,12-14H2,1H3;1H
• InChI key: SHAYBENGXDALFF-UHFFFAOYSA-N
• 유전자 정보: human ... HTR2A(3356), HTR2B(3357), HTR2C(3358), SLC6A2(6530), SLC6A4(6532)

설명

생화학적/생리학적 작용

Tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter (K_i = 3.4 nM) than the serotonin transporter (K_i = 161 nM). 5-HT₂ serotonin receptor antagonist.

특징 및 장점

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves