N8010

4-Nitrophenyl 4-guanidinobenzoate hydrochloride

protease substrate, ≥95.0% (TLC), powder

• 동의어(들): 4-Guanidinobenzoic acid 4-nitrophenylester hydrochloride, NPGB, pNPGB
• 실험식(Hill 표기법): C₁₄H₁₂N₄O₄ · HCl
• CAS Number: 19135-17-2
• Molecular Weight: 336.73
• Beilstein: 8024554
• EC Number: 242-831-3
• MDL number: MFCD00037010
• UNSPSC 코드: 12352204
• PubChem Substance ID: 24897847
• NACRES: NA.32

속성

• Product Name: 4-Nitrophenyl 4-guanidinobenzoate hydrochloride, protease inhibitor and substrate
• Quality Level: 200
• 분석: ≥95.0% (TLC)
• 양식: powder
• solubility: formic acid: soluble 49.00-51.00 mg/mL
• 저장 온도: −20°C
• SMILES string: Cl[H].NC(=N)Nc1ccc(cc1)C(=O)Oc2ccc(cc2)[N+]([O-])=O
• InChI: 1S/C14H12N4O4.ClH/c15-14(16)17-10-3-1-9(2-4-10)13(19)22-12-7-5-11(6-8-12)18(20)21;/h1-8H,(H4,15,16,17);1H
• InChI key: PKSBDZOBYIKNGY-UHFFFAOYSA-N

설명

일반 설명

4-Nitrophenyl 4-guanidinobenzoate hydrochloride (pNPGB) is a trypsin substrate. It is more water-soluble than 4-methylumbelliferyl 4-guanidinobenzoate and is preferred in spectrophotometric assay.

애플리케이션

4-Nitrophenyl 4-guanidinobenzoate hydrochloride has been used:

• as a substrate for trypsin for active site titration experiments
• for pre-treating of mosquito eggs in the interplasmid transposition assay
• as a component of isotonic buffer to moisten filter paper for mosquito embryo collection

생화학적/생리학적 작용

4-Nitrophenyl 4-guanidinobenzoate hydrochloride (pNPGB) inhibits phenoloxidase enzyme and delays embryo chorionic membrane hardening.

안전성 정보

• 픽토그램: GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H318
• 예방조치 성명서: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves