P7754

5α-Pregnane-3,20-dione (allo)

progesterone metabolite

• 동의어(들): 5α-Dihydroprogesterone, Allopregnane-3,20-dione
• 실험식(Hill 표기법): C₂₁H₃₂O₂
• CAS Number: 566-65-4
• Molecular Weight: 316.48
• EC Number: 209-297-3
• MDL number: MFCD00067132
• UNSPSC 코드: 51111800
• PubChem Substance ID: 24898872
• NACRES: NA.77

속성

• Quality Level: 200
• 양식: powder
• SMILES string: [H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](C(C)=O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CCC(=O)C2
• InChI: 1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14,16-19H,4-12H2,1-3H3/t14-,16-,17+,18-,19-,20-,21+/m0/s1
• InChI key: XMRPGKVKISIQBV-BJMCWZGWSA-N

설명

생화학적/생리학적 작용

A high-level metabolite of progesterone in breast cancer tissue (but not normal breast tissue); promotes cell proliferation and detachment. Receptors appear only on the cell surface of MCF-7 breast cancer cells, not on nuclei where most other steroid receptors are located.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)