S1542

Anti-Substance P antibody produced in rabbit

whole antiserum

• 동의어(들): Anti-SP
• MDL number: MFCD00162870
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: whole antiserum
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 포함: 15 mM sodium azide
• 종 반응성: human, pig, bovine, rat, cat, monkey
• 기술: dot blot: 1:20,000; radioimmunoassay: 1:5,000
• UniProt 수납 번호: P20366
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... TAC1(6863) ; rat ... Tac1(24806)

설명

일반 설명

Substance P (SP) is a 11 amino acid peptide. It is a member of tachykinins family, that includes neurokinin A, neurokinin B, neuropeptide K, neuropeptide Y and hemokinin-1 It is located on human chromosome 7q21.3.

Substance P (SP) is widely distributed throughout the central nervous system (CNS) and peripheral nervous system, including the brain, spinal cord, primary sensory neurons and intrinsic nerve fibers associated with the gastrointestinal (GI) tract.

면역원

synthetic Substance P (SP), conugated to KLH.

애플리케이션

Anti-Substance P antibody has been used in immunostaining and immunohistochemistry.

생화학적/생리학적 작용

Substance P (SP) improves the multiplication and paracrine ability of stem cells acquired from adipose in vitro. It participates in the movement of several organ tracts, trigger glandular secretion and controls autonomic reflexes. It plays an important role in neuroimmune and systemic autoimmune/inflammatory conditions like multiple sclerosis (MS), rheumatoid arthritis, inflammatory bowel disease and also in infections and cancer.

Substance P (SP) is a neurotransmitter or neuromodulator. SP mediates the process of neurogenic inflammation.

분석 메모

The antiserum is evaluated for activity and specificity by dot blot immunoassay and RIA.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable