S4776

Somatotropin from human pituitary

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), lyophilized powder

• 동의어(들): Growth Hormone, STH
• MDL number: MFCD00081960
• UNSPSC 코드: 51111800
• NACRES: NA.32

속성

• 생물학적 소스: human
• Quality Level: 200
• 재조합: expressed in E. coli
• 무균: non-sterile
• 분석: ≥95% (SDS-PAGE)
• 양식: lyophilized powder
• 효능: 0.025-0.1 ng/mL cell proliferation using Nb2-11 cells per bioactivity ED₅₀
• 분자량: predicted mol wt ~22 kDa
• drug control: Home Office Schedule 4.2
• 불순물: endotoxin, tested
• solubility: PBS: 0.100 mL, clear, colorless (with 0.1% BSA )
• UniProt 수납 번호: P01241; P10912
• 배송 상태: ambient
• 저장 온도: −20°C
• 유전자 정보: human ... GH1(2688), GHR(2690)

설명

일반 설명

Somatotropin or growth hormone is a peptide hormone that is secreted by the anterior pituitary gland. It is essential for growth. The hormone increases muscle mass, reduces fat mass, helps in maintaining normal blood glucose levels and also promotes a balanced lipid profile.

애플리케이션

Somatotropin or growth hormone has been used to study the molecular interactions of ephrin type-A receptor 4 precursor (EphA4) with the growth hormone receptor. It has also been used to induce differentiation in mammary epithelial cell line HC11.

생화학적/생리학적 작용

Increases mass of most tissues by increasing cell number rather than cell size, mobilizes fat stores.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in TBS (20 mM Tris, 0.15 M NaCl, pH 8.5) containing 50 μg of BSA per 1 μg of cytokine.

재구성

It is recommended that sterile PBS containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of no less than 10 μg/mL.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable