S9311

SIB 1893

>99%, solid

• 동의어(들): [E]-2-Methyl-6-[2-phenylethenyl]pyridine
• 실험식(Hill 표기법): C₁₄H₁₃N
• CAS Number: 7370-21-0
• Molecular Weight: 195.26
• MDL number: MFCD02262120
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278718
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: >99%
• 양식: solid
• solubility: DMSO: 18 mg/mL
• 저장 온도: 2-8°C
• SMILES string: Cc1cccc(\C=C\c2ccccc2)n1
• InChI: 1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+
• InChI key: SISOFUCTXZKSOQ-ZHACJKMWSA-N
• 유전자 정보: human ... GRM1(2911), GRM5(2915)

설명

애플리케이션

SIB 1893 may be used in mGluR5 metabotropic glutamate receptor-mediated cell signaling studies.

생화학적/생리학적 작용

SIB 1893 non-competitively inhibits glutamate-induced increase in Ca²⁺ at human metabotropic glutamate receptor 1 (hmGluR1).¹ It also acts as a positive allosteric modulator of hmGluR4.²

Selective and noncompetitive mGlu₅ metabotropic glutamate receptor antagonist.

특징 및 장점

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves