SML0033

Itopride hydrochloride

≥98% (HPLC)

• 동의어(들): N-[[4-[2-(Dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxy benzamidehydrochloride, N-[p-[2-(dimethylamino)ethoxy]benzyl]veratramide hydrochloride
• 실험식(Hill 표기법): C₂₀H₂₆N₂O₄ ·HCl
• CAS Number: 122892-31-3
• Molecular Weight: 394.89
• MDL number: MFCD00881710
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825103
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to tan
• solubility: H₂O: ≥48 mg/mL
• 주관자: Abbott
• 저장 온도: 2-8°C
• SMILES string: Cl.COc1ccc(cc1OC)C(=O)NCc2ccc(OCCN(C)C)cc2
• InChI: 1S/C20H26N2O4.ClH/c1-22(2)11-12-26-17-8-5-15(6-9-17)14-21-20(23)16-7-10-18(24-3)19(13-16)25-4;/h5-10,13H,11-12,14H2,1-4H3,(H,21,23);1H
• InChI key: ZTOUXLLIPWWHSR-UHFFFAOYSA-N

설명

일반 설명

Itopride hydrochloride is a new prokinetic drug.

생화학적/생리학적 작용

Antagonist of dopamine D2-receptor with anticholinesterase activity.

Itopride hydrochloride enhances the gastrointestinal motility by blocking the activity of dopamine on the D2 receptors, on the post-synaptic cholinergic nerves and by inducing the liberation of acetylcholine in the myenteric plexus. It also inhibits the hydrolysis of the released acetylcholine with the help of acetylcholinesterase.

Itopride is an acetylcholinesterase (AChE) inhibitor and D2 dopamine receptor antagonist. Itopride is used as a gastroprokinetic agent.

특징 및 장점

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS09
• 신호어: Warning
• 유해 및 위험 성명서: H410
• 예방조치 성명서: P273 - P391 - P501
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable