SML0038
Fluvastatin sodium hydrate
≥98% (HPLC)
동의어(들):
(±)-(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methyethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt hydrate
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
실험식(Hill 표기법):
C24H25FNO4 · Na · xH2O
CAS Number:
Molecular Weight:
433.45 (anhydrous basis)
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.77
추천 제품
Quality Level
분석
≥98% (HPLC)
양식
powder
저장 조건
desiccated
색상
white to tan
solubility
H2O: ≥9 mg/mL
주관자
Novartis
저장 온도
2-8°C
SMILES string
O.[Na+].CC(C)n1c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(-c2ccc(F)cc2)c3ccccc13
InChI
1S/C24H26FNO4.Na.H2O/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30;;/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30);;1H2/q;+1;/p-1/b12-11+;;/t18-,19-;;/m1../s1
InChI key
KKEMYLLTGGQWCE-PMRANXHDSA-M
관련 카테고리
애플리케이션
Fluvastatin sodium hydrate has been used:
- to examine its effect on β -glucan-induced training on immunity
- to investigate the effect of statins on the number of uncoupling protein 1 (UCP1)+ cells
- to determine its effect on insulin degrading enzyme (IDE) secretion from astrocytes
- to treat and study its effect on human umbilical vein endothelial cells (HUVECs) in vitro
Fluvastatin sodium hydrate has been used:
- to test its anti-hepatitis C virus (HCV) activity
- as a cholesterol inhibitor
- to study its effects on β-glucan-induced monocyte immune training
생화학적/생리학적 작용
Fluvastatin has antifungal activity.
Fluvastatin is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin is antilipemic and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.
특징 및 장점
This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
이미 열람한 고객
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.