SML0593

CGP52432

≥98% (HPLC)

• 동의어(들): [3-[[(3,4-Dichlorophenyl)methyl]amino]propyl](diethoxymethyl)-phosphinic acid
• 실험식(Hill 표기법): C₁₅H₂₄Cl₂NO₄P
• CAS Number: 139667-74-6
• Molecular Weight: 384.24
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to beige
• solubility: H₂O: 1 mg/mL, clear (warmed)
• 저장 온도: 2-8°C
• SMILES string: [P](=O)(O)(C(OCC)OCC)CCCNCc1cc(c(cc1)Cl)Cl
• InChI: 1S/C15H24Cl2NO4P/c1-3-21-15(22-4-2)23(19,20)9-5-8-18-11-12-6-7-13(16)14(17)10-12/h6-7,10,15,18H,3-5,8-9,11H2,1-2H3,(H,19,20)
• InChI key: GJZVQXWEIYRHBE-UHFFFAOYSA-N

설명

애플리케이션

CGP52432 has been used as a γ-aminobutyric acid B (GABA_B) antagonist:

• to study its effects on the simulation of the onset of status epilepticus (SE) in mice
• for voltage-clamp recording in mice neurons
• to study its effects on the GABA_B receptor-mediated neurotransmission in guinea pig hippocampus

생화학적/생리학적 작용

CGP52432 is a very potent antagonist of GABA_B receptors.

CGP52432 is a very potent antagonist of GABA_B receptors. (IC₅₀ = 85 nM).

CGP52432 participates in inhibiting the glycine overflow in the hippocampus.

특징 및 장점

This compound is featured on the GABAB Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

기타 정보

Do not freeze.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable