SML0987

CCG-1423

≥98% (HPLC)

• 동의어(들): CCG 1423, N-[2-[(4-Chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)-benzamide
• 실험식(Hill 표기법): C₁₈H₁₃ClF₆N₂O₃
• CAS Number: 285986-88-1
• Molecular Weight: 454.75
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 5 mg/mL, clear (warmed)
• 저장 온도: 2-8°C
• SMILES string: FC(F)(F)c1cc(cc(c1)C(=O)NOC(C)C(=O)Nc2ccc(cc2)Cl)C(F)(F)F
• InChI: 1S/C18H13ClF6N2O3/c1-9(15(28)26-14-4-2-13(19)3-5-14)30-27-16(29)10-6-11(17(20,21)22)8-12(7-10)18(23,24)25/h2-9H,1H3,(H,26,28)(H,27,29)
• InChI key: DSMXVSGJIDFLKP-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

CCG-1423 is a potent and specific inhibitor of Rho pathway signaling and activation of serum response factor (SRF) transcription.

CCG-1423 is a potent and specific inhibitor of Rho pathway signaling and activation of serum response factor (SRF) transcription. CCG-1423 inhibits SRF-driven luciferase expression in PC-3 cells following stimulation with constitutively active Gα13. Also CCG-1423 selectively inhibits DNA synthesis, proliferation and invasion of Rho-overexpressing cell lines.

특징 및 장점

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안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable