SML1077

ML298

≥98% (HPLC)

• 동의어(들): 3,4-Difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-benzamide, CID53393915
• 실험식(Hill 표기법): C₂₂H₂₃F₃N₄O₂
• CAS Number: 1426916-02-0
• Molecular Weight: 432.44
• UNSPSC 코드: 41106300
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 20 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: Fc1c(ccc(c1)C(=O)NCCN2CCC3(N(CNC3=O)c4cc(ccc4)F)CC2)F
• InChI: 1S/C22H23F3N4O2/c23-16-2-1-3-17(13-16)29-14-27-21(31)22(29)6-9-28(10-7-22)11-8-26-20(30)15-4-5-18(24)19(25)12-15/h1-5,12-13H,6-11,14H2,(H,26,30)(H,27,31)
• InChI key: XAPVAKKLQGLNOY-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

ML298 is a Phospholipase D2 (PLD2) inhibitor.

ML298 is a potent, specific inhibitor of Phospholipase D2 (PLD2; IC₅₀ = 355 nM). ML298 does not affect PLD1 activity at concentrations up to 20 μM.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable