추천 제품
분석
≥98% (HPLC)
양식
powder
색상
white to beige
solubility
DMSO: 2 mg/mL, clear
저장 온도
2-8°C
SMILES string
[nH]1[c](c(ccc1)C(=O)NCCCNC(=O)c2n[o]c(c2)c3ccccc3)=O
InChI key
NNNDNXLMQAPQQQ-UHFFFAOYSA-N
생화학적/생리학적 작용
ML327 is a regulator of E-cadherin transcription that restores E-cadherin expression in cancer cell lines and partially reverses Epithelial-to-Mesenchymal Transition (EMT). It is a potent inducer of mesenchymal-to-epithelial transition (MET) in epithelial cancers. Apparently ML327 blocks MYC expression in neuroblastomas. It induces apoptosis in cancer cells and sensitizes Ewing sarcoma cells to TRAIL.
regulator of E-cadherin transcription that restores E-cadherin expression in cancer cell lines; inducer of mesenchymal-to-epithelial transition (MET)
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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