SML3431

JBSNF-000088

≥98% (HPLC)

• 동의어(들): 6-Methoxy-3-pyridinecarboxamide, 6-Methoxyniacinamide, 6-Methoxynicotinamide, NSC 70628
• 실험식(Hill 표기법): C₇H₈N₂O₂
• CAS Number: 7150-23-4
• Molecular Weight: 152.15
• MDL number: MFCD00229166
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: NC(=O)c1cnc(cc1)OC
• InChI: 1S/C7H8N2O2/c1-11-6-3-2-5(4-9-6)7(8)10/h2-4H,1H3,(H2,8,10)
• InChI key: KXDSMFBEVSJYRF-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

JBSNF-000088 is a cell penetrant, potent and selective inhibitor of Nicotinamide N-methyltransferase (NNMT) that reduces 1-methyl-nicotinamide (MNA) and improved glucose control in mice models of metabolic disease. JBSNF-000088 potently inhibits growth of PFA ependymoma cells.

cell penetrant, potent and selective inhibitor of Nicotinamide N-methyltransferase (NNMT)

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H319
• 예방조치 성명서: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable