T4580

Tiludronate disodium salt hydrate

≥98% (HPLC)

• 동의어(들): Skelid, Tiludronic acid disodium, [[(4-Chlorophenyl)thio]methylene]bisphosphonic acid disodium salt hydrate
• 실험식(Hill 표기법): C₇H₇ClNa₂O₆P₂S · xH₂O
• CAS Number: 89987-06-4
• Molecular Weight: 362.57 (anhydrous basis)
• MDL number: MFCD16872037
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329826798
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to off-white
• solubility: H₂O: >10 mg/mL, clear
• 주관자: Sanofi Aventis
• SMILES string: O.[Na+].[Na+].OP([O-])(=O)C(Sc1ccc(Cl)cc1)P(O)([O-])=O
• InChI: 1S/C7H9ClO6P2S.2Na.H2O/c8-5-1-3-6(4-2-5)17-7(15(9,10)11)16(12,13)14;;;/h1-4,7H,(H2,9,10,11)(H2,12,13,14);;;1H2/q;2*+1;/p-2
• InChI key: SZVJRJRMQCKFON-UHFFFAOYSA-L

설명

생화학적/생리학적 작용

Tiludronate is a bisphosphonate bone resorption inhibitor. Tiludronate inhibits protein-tyrosine-phosphatase, leading to detachment of osteoclasts from the bone surface. It also inhibits the osteoclastic proton pump and is used to treat Paget′s disease.

특징 및 장점

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

제조 메모

Tiludronate disodium salt hydrate is soluble in DMSO at a concentration that is greater than or equal to 10 mg/ml.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable