T7375

Thionicotinamide adenine dinucleotide

≥90%

• 동의어(들): Thionicotinamide-DPN
• Linear Formula: C₂₁H₂₇N₇O₁₃SP₂
• CAS Number: 4090-29-3
• Molecular Weight: 679.49
• MDL number: MFCD00079609
• UNSPSC 코드: 41106305
• PubChem Substance ID: 24900446
• NACRES: NA.51

속성

• Quality Level: 200
• 분석: ≥90%
• 저장 온도: −20°C
• SMILES string: NC(=S)C1=CC=C[N](=C1)C2OC(COP(O)(=O)OP(O)(=O)OCC3OC(C(O)C3O)n4cnc5c(N)ncnc45)C(O)C2O
• InChI: 1S/C21H28N7O13P2S/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(40-21)6-38-43(35,36)41-42(33,34)37-5-10-13(29)15(31)20(39-10)27-3-1-2-9(4-27)18(23)44/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H2,23,44)(H,33,34)(H,35,36)(H2,22,24,25)
• InChI key: JFOSDPGFZXVRDA-UHFFFAOYSA-N

설명

애플리케이션

Thionicotinamide adenine dinucleotide has been used as a substrate analog in S-adenosyl-l-homocysteine (AdoHcy) hydrolases (SAHH) inhibition assay and in NAD⁺ glycohydrolase activity.

생화학적/생리학적 작용

Thionicotinamide adenine dinucleotide (sNAD) is an analog of coenzyme nicotinamide adenine dinucleotide (NAD) and NADH. sNAD is a potential inhibitor of NAD⁺ kinase. NAD⁺ kinase modulates NAD levels, contributing to cytotoxicity in cancer cells.

결합

Analog of NAD

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable