50632-U

Ascentis^® Express 90 Å F5 (5 μm) HPLC Columns

L × I.D. 25 cm × 4.6 mm, HPLC Column

• 동의어(들): Core-shell (SPP) Fused Core PFP HPLC column
• UNSPSC 코드: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

속성

• Product Name: Ascentis^® Express F5, 5 μm HPLC Column, 5 μm particle size, L × I.D. 25 cm × 4.6 mm
• material: stainless steel column
• Quality Level: 100
• Agency: suitable for USP L43
• 제품 라인: Ascentis^®
• 특징: endcapped
• 제조업체/상표: Ascentis^®
• 포장: 1 ea of
• 파라미터: 60 °C temp. range; 600 bar max. pressure (9000 psi)
• 기술: HPLC: suitable; LC/MS: suitable
• 길이 × I.D.: 25 cm × 4.6 mm
• 표면적: 90 m²/g
• 불순물: <5 ppm metals
• Matrix: Fused-Core particle platform; superficially porous particle
• 기질 활성군: PFP (pentafluorophenyl) phase
• 입자 크기: 5 μm
• 공극 크기: 90 Å pore size
• 작동 pH: 2-8
• 응용 분야: food and beverages
• 분리 기술: reversed phase

설명

일반 설명

Ascentis^® Express 5 μm F5 is a high-speed, high-performance liquid chromatography column based on the highly efficient Fused-Core^® particle design. The bonded, endcapped, dimethylpentafluorophenyl-propylsilane stationary phase of Ascentis Express 5 μm F5 provides a stable, reversed-phase packing with electron-deficient phenyl rings due to the presence of electronegative fluorines. In addition to forming π-π and mildly steric interactions, F5 phases also retain compounds by polar interactions. As a result of having both polar and non-polar character, F5 phases can show dual-mode retention behavior, sometimes producing a “U-shaped” retention as a function of acetonitrile content of the mobile phase, with retention increasing at both low and high concentrations of ACN (reversed-phase and HILIC retention modes). Ascentis Express 5 μm F5 can be used for basic, acidic, or neutral compounds with alternate selectivity from C18.

애플리케이션

• Liquid chromatographic determination of lumacaftor in the presence of ivacaftor and identification of five novel degradation products using high-performance liquid chromatography ion trap time-of-flight mass spectrometry.: This study employs an Ascentis^® Express F5, 5 µm HPLC column for the precise determination of lumacaftor amidst ivacaftor and identifies novel degradation products, showcasing the column′s efficacy in complex mixture analysis (Özcan et al., 2023).


• Stability-indicating LC-MS/MS and LC-DAD methods for robust determination of tasimelteon and high resolution mass spectrometric identification of a novel degradation product.: Utilizing the Ascentis^® Express F5, 5 µm HPLC column, this research developed stability-indicating methods for tasimelteon, highlighting the column′s robustness in pharmaceutical analysis (Özcan et al., 2020).


• Recent trends in ultra-fast HPLC: new generation superficially porous silica columns.: This review explores the advancements in HPLC columns, including the Ascentis^® Express F5, emphasizing its role in achieving ultra-fast separations in analytical chemistry (Ali et al., 2012).

추천 제품

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

법적 정보

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

Fused-Core is a registered trademark of Advanced Materials Technology, Inc.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable