ALD00606
Wang−Yu non-directed C−H functionalization ligand
95%
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About This Item
Empirical Formula (Hill Notation):
C7H3F6NO
CAS Number:
Molecular Weight:
231.10
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.22
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Assay
95%
form
powder or crystals
reaction suitability
reaction type: C-C Bond Formation
reagent type: catalyst
reaction type: C-H Activation
mp
145 °C
storage temp.
−20°C
SMILES string
FC(F)(F)c1c(ncc(c1)C(F)(F)F)O
InChI key
IWSJDZMIJFAEBO-UHFFFAOYSA-N
Application
This 2-pyridone ligand developed in the laboratory of Jin-Quan Yu binds to palladium and accelerates non-directed C-H functionalization. Developed for C-H olefination and carboxylation with arene as the limiting reagent, the Wang-Yu ligand enables diversification of drugs, synthetic intermediates, and other bioactive small molecules.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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