850104P

18:0 Lyso PI

1-stearoyl-2-hydroxy-sn-glycero-3-phosphoinositol (ammonium salt), powder

• Synonym(s): 1-octadecanoyl-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt); PI(18:0/0:0); 110719
• Empirical Formula (Hill Notation): C₂₇H₅₆NO₁₂P
• CAS Number: 849412-49-3
• Molecular Weight: 617.71
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• Assay: >99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC)
• form: powder
• packaging: pkg of 1 × 100 μg (with stopper and crimp cap (850104P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850104P-500ug))
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 850104P
• lipid type: phosphoglycerides
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+]
• InChI: 1S/C27H53O12P.H3N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(29)37-18-20(28)19-38-40(35,36)39-27-25(33)23(31)22(30)24(32)26(27)34;/h20,22-28,30-34H,2-19H2,1H3,(H,35,36);1H3/t20-,22-,23-,24+,25-,26-,27-;/m1./s1
• InChI key: QVEDYTZLCBLSCH-FJYNCLFYSA-N

Description

General description

Lysophosphatidylinositol (LPI), an acidic lysophosholipid, carries inositol in its head group.

Application

18:0 Lyso PI (1-stearoyl-2-hydroxy-sn-glycero-3-phosphoinositol) has been used as lysophosphatidylinositol (LPI) substrate in lysophosphatidylinositol acyltransferase biochemical assay to determine lyso-phosphatidylinositol acyltransferase (LPIAT) activity of liver microsomes. It may be used as a synthetic LPI to compare its effects with liver LPI in transferrin (Tf) endocytosis. It may also be used as LPI standard to quantify serum LPI levels in gonadectomized rats.

Biochem/physiol Actions

Increased circulating levels of L-alpha-lysophosphatidylinositol (LPI) are associated with cancer and LPI is a potent ligand for the G-protein-coupled receptor GPR55.

Lysophosphatidylinositol (LPI) displays mitogenic activity and can serve as a bioactive lysophospholipid mediator. It may be considered as a lipid mediator.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850104P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850104P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids