870817P

N-palmitoylglycine

Avanti Research^™ - A Croda Brand

• Synonym(s): Glycine, N-(1-oxohexadecyl)-
• Empirical Formula (Hill Notation): C₁₈H₃₅NO₃
• CAS Number: 2441-41-0
• Molecular Weight: 313.48
• MDL number: MFCD00153471
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: powder
• packaging: pkg of 1 × 10 mg (870817P-10mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• lipid type: neutral glycerides; neutral lipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O=C(CCCCCCCCCCCCCCC)NCC(O)=O
• InChI: 1S/C18H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(20)19-16-18(21)22/h2-16H2,1H3,(H,19,20)(H,21,22)
• InChI key: KVTFEOAKFFQCCX-UHFFFAOYSA-N

Description

General description

N-palmitoylglycine belongs to the family of acyl amides, which are endogenous lipids with a potential to modulate pain and inflammation. Structurally, N-palmitoylglycine (PalGly) comprises 16-carbon saturated fatty acid attached to glycine through amide linkage. It is a structural analog of phospholipid-derived N-acyl ethanolamine. N-palmitoylglycine, a saturated lipid is endogenously produced at high levels in rat skin and spinal cord.

Application

N-palmitoylglycine has been used as an intact polar lipid (IPL) standard for determination of δ 15N values of nitrogen containing headgroups of IPLs using gas chromatography/combustion/isotope-ratio mass spectrometry.

Biochem/physiol Actions

N-palmitoylglycine stimulates calcium influx and nitric oxide (NO) production through calcium-sensitive nitric-oxide synthase in sensory neurons. It acts as a lipid activator of G-protein-coupled receptor GPR132.

Packaging

5 mL Amber Glass Screw Cap Vial (870817P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable