890703C

18:0 EPC (Cl Salt)

Avanti Research^™ - A Croda Brand 890703C

• Synonym(s): 1,2-distearoyl-sn-glycero-3-ethylphosphocholine (chloride salt)
• Empirical Formula (Hill Notation): C₄₆H₉₃NO₈PCl
• CAS Number: 328268-13-9
• Molecular Weight: 854.66
• MDL number: MFCD22495358
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: liquid
• packaging: pkg of 1 × 2.5 mL (890703C-25mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 890703C
• concentration: 10 mg/mL (890703C-25mg)
• lipid type: cationic lipids; transfection
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)OCC.[Cl-]
• InChI: 1S/C46H93NO8P.ClH/c1-7-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-45(48)51-42-44(43-54-56(50,52-9-3)53-41-40-47(4,5)6)55-46(49)39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-8-2;/h44H,7-43H2,1-6H3;1H/q+1;/p-1/t44-,56?;/m1./s1
• InChI key: ZVWMOQRUUFNEHD-UFOBXVRVSA-M

Description

Application

1,2-distearoyl-sn-glycero-3-ethylphosphocholine (18:0 EPC) might be used:

• to study its effect on the synergistic antimicrobial action of eugenol against Escherichia coli C600
• to test its use in the formation of lipid nanoparticle variants
• as a constituent of the microbubble formulation
• to prepare lipid monolayer for the study on the nature and orientation of interaction between graphene oxide (GO) and lipid models

Biochem/physiol Actions

Cationic lipids are useful as co-adjuvants to promote the immunogenicity of vaccines. 1,2-distearoyl-sn-glycero-3-ethylphosphocholine (18:0 EPC) is a cationic lipid and is found to upregulate cluster of differentiation (CD)80 and CD86 co-stimulatory molecules. The hydrophilic moiety and the acyl chains of the cationic lipids highly influences their co-stimulatory action.

Packaging

5 mL Clear Glass Sealed Ampule (890703C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H315,H319,H331,H336,H351,H361d,H372
• Precautionary Statements: P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Target Organs: Central nervous system
• WGK: WGK 3