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890703P

Avanti

18:0 EPC (Cl Salt)

Avanti Research - A Croda Brand 890703P, powder

Synonym(s):

1,2-distearoyl-sn-glycero-3-ethylphosphocholine (chloride salt)

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About This Item

Empirical Formula (Hill Notation):
C46H93NO8PCl
CAS Number:
Molecular Weight:
854.66
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 25 mg (890703P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 890703P

lipid type

transfection
cationic lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)OCC.[Cl-]

InChI

1S/C46H93NO8P.ClH/c1-7-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-45(48)51-42-44(43-54-56(50,52-9-3)53-41-40-47(4,5)6)55-46(49)39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-8-2;/h44H,7-43H2,1-6H3;1H/q+1;/p-1/t44-,56?;/m1./s1

InChI key

ZVWMOQRUUFNEHD-UFOBXVRVSA-M

Application

1,2-distearoyl-sn-glycero-3-ethylphosphocholine (18:0 EPC) might be used:
  • to study its effect on the synergistic antimicrobial action of eugenol against Escherichia coli C600
  • to test its use in the formation of lipid nanoparticle variants
  • as a constituent of the microbubble formulation
  • to prepare lipid monolayer for the study on the nature and orientation of interaction between graphene oxide (GO) and lipid models

Biochem/physiol Actions

Cationic lipids are useful co-adjuvants for promoting the immunogenicity of vaccines. 1,2-distearoyl-sn-glycero-3-ethylphosphocholine (18:0 EPC) is a cationic lipid and is found to upregulate cluster of differentiation (CD)80 and CD86 co-stimulatory molecules. The hydrophilic moiety and the acyl chains of the cationic lipids highly influences their co-stimulatory action.

Packaging

5 mL Amber Glass Screw Cap Vial (890703P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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