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1.11587

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Potassium hydroxide solution

c(KOH) = 0.1 mol/l (0.1 N) in methanol, ready-to-use volumetric solution for titration for non-aqueous media, Titriplex®

Synonym(s):

KOH solution in methanol

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20 μG
CA$355.00

CA$355.00


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20 μG
CA$355.00

About This Item

UNSPSC Code:
12352305
NACRES:
NA.21

CA$355.00


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Product Name

Potassium hydroxide solution in methanol, c(KOH) = 0.1 mol/l (0.1 N), Titripur®

Quality Level

product line

Titripur®

form

liquid

autoignition temp.

455 °C (Methanol)

quality

Analyzed in our ISO 17025 accredited QC lab

expl. lim.

5.5-44 % (v/v) Methanol)

reaction suitability

reaction type: Acid-base reactions

concentration

0.1 M

technique(s)

titration: suitable

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SRP3040SRP3042SRP3027
biological source

human

biological source

human

biological source

human

biological source

human

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

assay

≥95% (HPLC), ≥95% (SDS-PAGE)

assay

≥95% (HPLC), ≥95% (SDS-PAGE)

assay

≥95% (HPLC), ≥95% (SDS-PAGE)

assay

≥98% (HPLC), ≥98% (SDS-PAGE)

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

form

lyophilized

form

lyophilized

form

lyophilized

form

lyophilized

mol wt

25.5 kDa

mol wt

23.4 kDa

mol wt

15.8 kDa

mol wt

6.2 kDa

Application


  • Snap-on Adaptor for Microtiter Plates to Enable Continuous-Flow Microfluidic Screening and Harvesting of Crystalline Materials: This study presents an innovative approach for microfluidic screening and harvesting, using a snap-on adapter for microtiter plates, enhancing the crystallization processes in research and development within pharmaceutical and material science applications (Coliaie et al., 2023).

  • A Novel Sample Preparation Method Using Rapid Nonheated Saponification Method for the Determination of Cholesterol in Emulsified Foods: Discusses a novel technique involving potassium hydroxide in methanol for rapidly preparing samples to determine cholesterol levels in food products, beneficial for environmental testing and food safety (Jeong et al., 2012).

  • Extended Release of Bevacizumab by Thermosensitive Biodegradable and Biocompatible Hydrogel: Research focusing on a biodegradable hydrogel for extended drug release, where potassium hydroxide in methanol plays a role in the hydrogel preparation, proving crucial in pharmaceutical applications (Wang et al., 2012).

  • Spectrophotometric and Fluorimetric Determination of Diazepam, Bromazepam, and Clonazepam in Pharmaceutical and Urine Samples: This study utilizes potassium hydroxide in methanol for the enhanced spectrophotometric and fluorimetric analysis of benzodiazepines in clinical and forensic testing scenarios (Salem et al., 2004).

Features and Benefits

Accreditation:
This volumetric solution is analyzed by our calibration laboratory D-K-15185-01-00 which is accredited according to DIN EN ISO/IEC 17025 for analysis of amount-of-substance concentrations in volumetric solutions by DAkkS (Deutsche Akkreditierungsstelle - German National Accreditation Body). The accreditation certificate can be found at www.sigmaaldrich.com/ISO17025.

Packaging

SKU-pack size numbers ending with a "3" are SmartChemicals with an RFID tag on the label for seamless data transfer to the instrument, e.g. xxxxxx1003 or xxxxxxx 4003. More information on www.sigmaaldrich.com/SmartChemicals

Linkage

Replaces: PX1498A-6; PX1498A-3

Analysis Note

Form liquid
Amount-of-substance concentration 0.0995 - 0.1005 mol/L
Measurement uncertainty ± 0.0003 mol/L
Traceability NIST SRM

The concentration is determined by volumetric titration and refers to 20°C.
The amount-of-substance concentration of this volumetric solution is traceable to a primary standard reference material (SRM) from the National Institute of Standards and Technology, Gaithersburg, USA (NIST SRM 84 potassium hydrogen phthalate) by means of volumetric standard potassium hydrogen phthalate (article number 1.02400), certified reference material according to ISO 17034, analyzed by our accredited calibration laboratory of Merck KGaA, Darmstadt, Germany according to DIN EN ISO/IEC 17025. The uncertainty is expressed as expanded measurement uncertainty with a coverage factor k=2 covering a confidence level of 95%.

Note: The titer is a correction factor to correct for variations of the volumetric solution, the titration equipment, the temperature and other laboratory conditions. For correct titration results it is recommended to determine a titer with the laboratory specific equipment and under laboratory specific conditions directly after opening a new bottle and at regular time intervals.

Legal Information

Titripur is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Met. Corr. 1 - Skin Irrit. 2 - STOT SE 1

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

44.6 °F

Flash Point(C)

7 °C


Certificates of Analysis (COA)

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Anthony A Portale et al.
PloS one, 10(11), e0142924-e0142924 (2015-11-21)
Fibroblast growth factor 23 (FGF23) is a potent regulator of phosphate (Pi) and vitamin D homeostasis. The transcription factor, early growth response 1 (egr-1), is a biomarker for FGF23-induced activation of the ERK1/2 signaling pathway. We have shown that ERK1/2
Richard G Boles
Handbook of Growth and Growth Monitoring in Health and Disease null
Interplay between vitamin D and the drug metabolizing enzyme CYP3A4.
Wang Z
The Journal of Steroid Biochemistry and Molecular Biology, 136, 54-58 (2013)
Fibroblast growth factor 23 and bone mineralisation.
Guo YC and Yuan Q
International Journal of Oral Science, 7(1), 8-13 (2015)
Klotho converts canonical FGF receptor into a specific receptor for FGF23.
Urakawa I
Nature, 444(7120), 770-774 (2006)

Articles

Fibroblast growth factors in cell culture and various growth factors for your research

Fibroblast growth factors in cell culture and various growth factors for your research

Chromatograms

suitable for GC

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