08449

Hemoglobin from bovine blood

suitable for microbiology

• Synonym(s): FO Growth Supplement, Bovine hemoglobin, Hb, Methemoglobin
• CAS Number: 9008-02-0
• MDL number: MFCD00131282
• UNSPSC Code: 41171614
• eCl@ss: 42030116
• NACRES: NA.85

Properties

• sterility: sterile
• Quality Level: 100
• form: powder
• shelf life: limited shelf life, expiry date on the label
• mol wt: M_r ~64500
• loss: <10% loss on drying
• UniProt accession no.: P01966; P02070; P02081; P06642; P06643
• application(s): environmental; food and beverages; microbiology
• storage temp.: 2-8°C
• suitability: Neisseria spp.
• Gene Information: cow ... HBA1(281221), HBB(280813), HBE2(513240), HBE4(513108), HBG(511735), alpha globin(512439)

Description

General description

Hemoglobin is present in the red-blood corpuscles (RBCs) of vertebrates. It is composed of a globular structure with four α-β sub-units.

Application

Hemoglobin from bovine blood has been used as a supplement in tryptone yeast extract salts and glucose (TYESG) agar for performing extracellular proteolytic activity of Flavobacterium psychrophilum. It has also been used as a standard in Raman spectrometry.

The solubility of α-elastin has been applied to construction of elastin-mimetic biomaterials.

Biochem/physiol Actions

Oxygen transporter, NO scavenger

Oxygen transporter. The Fe²⁺/Fe³⁺ balance is a physiological indicator of blood oxygenation; deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.

Packaging

1 piece contains 100 g hemoglobin powder

Caution

Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves