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Key Documents

SML2036

Sigma-Aldrich

Gigantol

≥98% (HPLC)

Synonym(s):

5-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-2-methoxyphenol, CID 3085362

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About This Item

Empirical Formula (Hill Notation):
C16H18O4
CAS Number:
Molecular Weight:
274.31
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

Assay

≥98% (HPLC)

form

oil

color

colorless to light brown

storage temp.

2-8°C

SMILES string

O(C)c1c(cc(cc1)CCc2cc(cc(c2)O)OC)O

InChI

1S/C16H18O4/c1-19-14-8-12(7-13(17)10-14)4-3-11-5-6-16(20-2)15(18)9-11/h5-10,17-18H,3-4H2,1-2H3

InChI key

SDXKZPQOVUDXIY-UHFFFAOYSA-N

Biochem/physiol Actions

Gigantol is a bibenzyl compound isolated from Dendrobium orchids (Dendrobium aphyllum, Dendrobium draconis, Dendrobium aurantiacum, etc.) that exhibits potent cytotoxic activity against several cancer cell lines. It inhibits the migratory behavior of non-small cell lung cancer cells. Gigantol inhibits galactose-induced formation of cataracts through repression of the gene expression and activity of AR and iNOS.
potent cytotoxic agent isolated from Dendrobium orchids.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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