112747

N-Acetylsulfanilyl chloride

98%

• Synonym(s): 4-Acetamidobenzenesulfonyl chloride
• Linear Formula: 4-(CH₃CONH)C₆H₄SO₂Cl
• CAS Number: 121-60-8
• Molecular Weight: 233.67
• Beilstein/REAXYS Number: 746676
• EC Number: 204-485-1
• MDL number: MFCD00007442
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847112
• NACRES: NA.22

Properties

• assay: 98%
• mp: 142-145 °C (dec.) (lit.)
• functional group: amide
• SMILES string: CC(=O)Nc1ccc(cc1)S(Cl)(=O)=O
• InChI: 1S/C8H8ClNO3S/c1-6(11)10-7-2-4-8(5-3-7)14(9,12)13/h2-5H,1H3,(H,10,11)
• InChI key: GRDXCFKBQWDAJH-UHFFFAOYSA-N

Description

General description

L-hydroxyproline has been derivatized with N-acetylsulfanilyl chloride and 5-chlorovaleric acid during the synthesis of the haptens HP1 and HP2.

Application

N-Acetylsulfanilyl chloride is used in the synthesis of N1,N1-dimethylsulfanilamide as the internal standard in the reaction. The reaction is used to determine tramadol and its O-desmethylated metabolite in blood plasma.

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H314,H335
• pcodes: P260 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Skin Corr. 1B - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges