177504

Hexadecanedioic acid

96%

• Synonym(s): Thapsic acid
• Linear Formula: HOOC(CH₂)₁₄COOH
• CAS Number: 505-54-4
• Molecular Weight: 286.41
• Beilstein/REAXYS Number: 1792831
• EC Number: 208-013-5
• MDL number: MFCD00002746
• UNSPSC Code: 12162002
• PubChem Substance ID: 24850364
• NACRES: NA.23

Properties

• assay: 96%
• mp: 120-123 °C (lit.)
• SMILES string: OC(=O)CCCCCCCCCCCCCCC(O)=O
• InChI: 1S/C16H30O4/c17-15(18)13-11-9-7-5-3-1-2-4-6-8-10-12-14-16(19)20/h1-14H2,(H,17,18)(H,19,20)
• InChI key: QQHJDPROMQRDLA-UHFFFAOYSA-N

Description

General description

Hexadecanedioic acid (HDDA), also known as thapsic acid, is a straight-chain aliphatic dicarboxylic acid with the molecular formula C₁₆H₃₀O₄. It features two carboxylic acid groups (-COOH) at each end of a saturated hydrocarbon chain, which imparts thermal stability, hydrophobicity, and biocompatibility to the polymers.

Application

Hexadecanedioic acid can be used:

• As a tracer (radiolabeled with Gallium-68), for cardiac metabolic imaging, enabling visualization of fatty acid metabolism in the heart during PET scans. Its biocompatibility and mimicry of natural fatty acid pathways enhance diagnostic assessments of cardiac function.
• As a precursor to prepare noncross-linked terpolyester via melt polycondensation. This material can be used to fabricate ecofriendly food packaging materials.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)