433101

2-Methylcinnamic acid, predominantly trans

99%

• Linear Formula: CH₃C₆H₄CH=CHCO₂H
• CAS Number: 2373-76-4
• Molecular Weight: 162.19
• EC Number: 219-150-5
• MDL number: MFCD00016841
• UNSPSC Code: 12352100
• PubChem Substance ID: 24867122
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 99%
• mp: 174-176 °C (lit.)
• functional group: carboxylic acid
• SMILES string: Cc1ccccc1\C=C\C(O)=O
• InChI: 1S/C10H10O2/c1-8-4-2-3-5-9(8)6-7-10(11)12/h2-7H,1H3,(H,11,12)/b7-6+
• InChI key: RSWBWHPZXKLUEX-VOTSOKGWSA-N

Description

General description

2-Methylcinnamic acid has been reported to exhibit strong anti-fungal activity against white-rot fungus Lenzites betulina and brown-rot fungus Laetiporus sulphureus. Hydrogenation of 2-methylcinnamic acid using Walphos ligands and their biferrocene analogs has been studied.

Application

2-Methylcinnamic acid may be used as starting reagent for the total synthesis of the cytotoxic alkaloid, 22-hydroxyacuminatine and for the preparation of (E)-2-methylcinnamic acid i-butylammonium salt.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)