441279

(1R)-(−)-2-Azabicyclo[2.2.1]hept-5-en-3-one

≥98%

• Empirical Formula (Hill Notation): C₆H₇NO
• CAS Number: 79200-56-9
• Molecular Weight: 109.13
• Beilstein/REAXYS Number: 4230721
• EC Number: 418-530-1
• MDL number: MFCD00211274
• UNSPSC Code: 12352005
• PubChem Substance ID: 24867649
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: ≥98%
• form: solid
• optical activity: [α]20/D −565°, c = 1 in chloroform
• optical purity: ee: 99% (HPLC)
• mp: 94-97 °C (lit.)
• SMILES string: O=C1N[C@@H]2C[C@H]1C=C2
• InChI: 1S/C6H7NO/c8-6-4-1-2-5(3-4)7-6/h1-2,4-5H,3H2,(H,7,8)/t4-,5+/m1/s1
• InChI key: DDUFYKNOXPZZIW-UHNVWZDZSA-N

Description

General description

(1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one is a bicyclic γ-lactam.

Application

(1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one can be used as a precursor to prepare:

• Amino-peramivir, a potent neuraminidase inhibitor.
• Five membered analogs of 4-amino-5-halopentanoic acids as potential GABA aminotransferase (GABA-AT) inactivators.

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H317,H318
• pcodes: P280 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves