441287

(1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one

≥98%

• Empirical Formula (Hill Notation): C₆H₇NO
• CAS Number: 130931-83-8
• Molecular Weight: 109.13
• MDL number: MFCD00211275
• UNSPSC Code: 12352005
• PubChem Substance ID: 24867650
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: ≥98%
• optical activity: [α]20/D +565°, c = 1 in chloroform
• optical purity: ee: 99% (HPLC)
• mp: 94-97 °C (lit.)
• SMILES string: O=C1N[C@H]2C[C@@H]1C=C2
• InChI: 1S/C6H7NO/c8-6-4-1-2-5(3-4)7-6/h1-2,4-5H,3H2,(H,7,8)/t4-,5+/m0/s1
• InChI key: DDUFYKNOXPZZIW-CRCLSJGQSA-N

Description

Application

This lactam and its antipode are precursors to the enantiomers of the carbocyclic nucleoside carbovir. It has been demonstrated that (-)-carbovir is a potent inhibitor of HIV-1 and based on clinical trials it could become an alternative to AZT. AZT is a trademark of The Wellcome Foundation Ltd.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves