556327

4-Bromophenyl methyl sulfone

97%

• Synonym(s): 1-Bromo-4-(methylsulfonyl)benzene
• Linear Formula: BrC₆H₄SO₂CH₃
• CAS Number: 3466-32-8
• Molecular Weight: 235.10
• EC Number: 222-421-0
• MDL number: MFCD00025065
• UNSPSC Code: 12352100
• PubChem Substance ID: 24879546
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 97%
• mp: 103-107 °C (lit.)
• functional group: bromo; sulfone
• SMILES string: CS(=O)(=O)c1ccc(Br)cc1
• InChI: 1S/C7H7BrO2S/c1-11(9,10)7-4-2-6(8)3-5-7/h2-5H,1H3
• InChI key: FJLFSYRGFJDJMQ-UHFFFAOYSA-N

Description

Application

4-Bromophenyl methyl sulfone may be used to synthesize:

• biaryl methyl sulfones
• 5-[[-4-(methylsulfonyl)phenyl]thio]thiophene-2-sulfonamide
• 1-[4-(methylsulfonyl)phenyl]-1H-pyrazole (Hmsppz)
• DuP 697 via reaction with (5-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl)trimethylsilane

4-Bromophenyl methyl sulfone (1-bromo-4-(methylsulfonyl)benzene) can undergo coupling reaction with benzene sulfonamide in the presence of copper(I)iodide to form the corresponding N-aryl sulfonamide.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)