Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

224M-1

Sigma-Aldrich

Beta-Catenin (14) Mouse Monoclonal Antibody

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
Pricing and availability is not currently available.

biological source

mouse

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

14, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (224M-14)
vial of 0.5 mL concentrate (224M-15)
bottle of 1.0 mL predilute (224M-17)
vial of 1.0 mL concentrate (224M-16)
bottle of 7.0 mL predilute (224M-18)

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
420M-1MABF316104-958
Beta-Catenin (14) Mouse Monoclonal Antibody

224M-1

Beta-Catenin (14) Mouse Monoclonal Antibody

p120 Catenin (MRQ-5) Mouse Monoclonal Antibody

420M-1

p120 Catenin (MRQ-5) Mouse Monoclonal Antibody

Anti-β-Catenin Antibody, clone 12F7

MABF3161

Anti-β-Catenin Antibody, clone 12F7

Anti-Beta Catenin Antibody, clone 7F7.2 clone 7F7.2, Upstate®, from mouse

04-958

Anti-Beta Catenin Antibody, clone 7F7.2

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

antibody form

culture supernatant

antibody form

culture supernatant

antibody form

purified antibody

antibody form

purified immunoglobulin

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

rat, mouse, human

clone

14, monoclonal

clone

MRQ-5, monoclonal

clone

12F7, monoclonal

clone

7F7.2, monoclonal

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

-

General description

Beta-Catenin is a 92 kD protein normally found in the cytoplasm of the cell in the submembranous location. This protein is associated with E-Cadherin and may be essential for the function of E-Cadherin. Mutations in the Beta-Catenin gene result in nuclear accumulation of this protein. Nuclear accumulation of this protein has been demonstrated in fibromatosis lesions of the breast and abdomen and therefore is useful in differentiating this lesion from other spindle cell lesions that may occur in these locations. Nuclear accumulation of Beta-Catenin has also been demonstrated in colorectal carcinoma.

Quality


IVD
IVD
IVD
RUO

Linkage

Beta-Catenin Positive Control Slides, Product No. 224S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our Product Selector Tool.

  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    0000286170
    0000286170
    1425806A-Z

    Don't see the Right Version?

    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

    Search for a COA

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Wei Min et al.
    The American journal of Chinese medicine, 42(3), 709-727 (2014-05-30)
    Ultraviolet A (UVA) radiation contributes to skin photoaging. Baicalin, a plant-derived flavonoid, effectively absorbs UV rays and has been shown to have anti-oxidant and anti-inflammatory properties that may delay the photoaging process. In the current study, cultured human skin fibroblasts
    Jia-Ming Xie et al.
    Cancer research, 74(18), 5127-5138 (2014-08-03)
    The p53-induced glycolysis and apoptosis regulator (TIGAR) inhibits glycolysis, resulting in higher intracellular NADPH, lower reactive oxygen species (ROS) and autophagy activity. In this study, we investigated whether TIGAR might exert dual impacts on cancer cell survival based on its
    Timothy S Pardee et al.
    Oncotarget, 5(12), 4170-4179 (2014-06-26)
    F10 is an oligonucleotide based on the thymidylate synthase (TS) inhibitory 5-fluorouracil (5-FU) metabolite, 5-fluoro-2'-deoxyuridine-5'-O-monophosphate. We sought to determine the activity of F10 against preclinical models of acute lymphoblastic leukemia (ALL). F10 treatment resulted in robust induction of apoptosis that
    C Leufke et al.
    Oncogene, 33(27), 3506-3518 (2013-08-21)
    The incidence of skin cancer is increasing worldwide and cutaneous squamous cell carcinomas (SCCs) are associated with considerable morbidity and mortality, particularly in immunosuppressed individuals ('carcinomatous catastrophy'). Yet, molecular mechanisms are still insufficiently understood. Besides ultraviolet (UV)-indicative mutations, chromosomal aberrations
    Maja T Tomicic et al.
    Cancer research, 74(19), 5585-5596 (2014-08-16)
    DNA repair processes are a key determinant of the sensitivity of cancer cells to DNA-damaging chemotherapeutics, which may induce certain repair genes as a mechanism to promote resistance. Here, we report the results of a screen for repair genes induced
    View All Related Papers

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service