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57858

Sigma-Aldrich

Sodium iodoacetate

BioUltra, ≥99.5% (NT)

Synonym(s):

Iodoacetic acid sodium salt

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About This Item

Linear Formula:
ICH2COONa
CAS Number:
Molecular Weight:
207.93
Beilstein/REAXYS Number:
4009322
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.26

Pricing and availability is not currently available.

product line

BioUltra

Quality Level

assay

≥99.5% (NT)

impurities

insoluble matter, passes filter test
≤0.5% water

mp

208 °C (dec.) (lit.)

solubility

methanol: 0.1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤100 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤500 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

absorption

cut-off at 335 nm in methanol at 0.1 M

storage temp.

−20°C

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1 of 4

This Item
I9148I251271183
assay

≥99.5% (NT)

assay

≥98%

assay

≥98%

assay

≥99.0% (NT)

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

solubility

methanol: 0.1 M at 20 °C, clear, colorless

solubility

H2O: 0.5 M, clear, colorless

solubility

H2O: 100 mg/mL

solubility

H2O: 3 M at 20 °C, clear, colorless

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

mp

208 °C (dec.) (lit.)

mp

208 °C (dec.) (lit.)

mp

208 °C (dec.) (lit.)

mp

>300 °C (dec.) (lit.)

cation traces

Al: ≤5 mg/kg, Ba: ≤5 mg/kg, Ca: ≤10 mg/kg, Co: ≤5 mg/kg, Cu: ≤5 mg/kg, K: ≤500 mg/kg, Mg: ≤5 mg/kg, Mo: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg, As: ≤0.1 mg/kg, Cd: ≤5 mg/kg, Fe: ≤5 mg/kg, Mn: ≤5 mg/kg, Sr: ≤5 mg/kg

cation traces

Al: ≤0.0005%, Ca: ≤0.001%, Cu: ≤0.001%, Fe: ≤0.0005%, K: ≤0.02%, Mg: ≤0.0005%, NH4+: ≤0.05%, Pb: ≤0.001%, Zn: ≤0.0005%

cation traces

-

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤10 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤200 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤10 mg/kg, Zn: ≤5 mg/kg

Application

Reagent for the modification of cysteine residues in proteins.
Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.
Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.

Other Notes

Sulfhydryl reagent[1][2]

pictograms

Skull and crossbonesCorrosion

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

406.4 °F

flash_point_c

208 °C

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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