I9148

Sodium iodoacetate

powder, ≥98%

• Synonym(s): Iodoacetic acid sodium salt
• Linear Formula: ICH₂COONa
• CAS Number: 305-53-3
• Molecular Weight: 207.93
• Beilstein/REAXYS Number: 4009322
• EC Number: 206-165-7
• MDL number: MFCD00002686
• UNSPSC Code: 12352202
• PubChem Substance ID: 24896151
• NACRES: NA.77

Properties

• Product Name: Sodium iodoacetate, ≥98%, BioUltra
• biological source: synthetic (organic)
• Quality Level: 200
• product line: BioUltra
• assay: ≥98%
• form: powder
• impurities: ≤0.0005% Phosphorus (P); ≤0.1% Insoluble matter
• mp: 208 °C (dec.) (lit.)
• solubility: H₂O: 0.5 M, clear, colorless
• anion traces: sulfate (SO₄^2-): ≤0.05%

Description

Application

Reagent for the modification of cysteine residues in proteins.

Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.

Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.

Safety Information

• pictograms: GHS06,GHS05
• signalword: Danger
• hcodes: H301,H314
• pcodes: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 406.4 °F
• flash_point_c: 208 °C
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges