C2671

Corticotropin Releasing Factor bovine

≥90% (HPLC), Synthetic

• Synonym(s): CRF, CRH
• Empirical Formula (Hill Notation): C₂₀₆H₃₄₀N₆₀O₆₃S
• CAS Number: 92307-52-3
• Molecular Weight: 4697.33
• MDL number: MFCD00081537
• UNSPSC Code: 12352202
• NACRES: NA.32

Properties

• Quality Level: 200
• assay: ≥90% (HPLC)
• form: powder
• UniProt accession no.: Q95MI6
• storage temp.: −20°C
• Gene Information: cow ... CRH(280755)

Description

Amino Acid Sequence

Ser-Gln-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Thr-Lys-Ala-Asp-Gln-Leu-Ala-Gln-Gln-Ala-His-Asn-Asn-Arg-Lys-Leu-Leu-Asp-Ile-Ala

Biochem/physiol Actions

CRF is a hypothalamic peptide that releases ACTH and endorphin from the anterior pituitary. It is also a neurotransmitter in the central nervous system, and is involved in autonomic and endocrine responses to stress.

Releases ACTH and endorphin from the anterior pituitary; central nervous system neurotransmitter.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)