E1752

Estrone 3-(β-D-glucuronide) sodium salt

• Synonym(s): 1,3,5(10)-Estratrien-17-one 3-glucuronide sodium salt
• Empirical Formula (Hill Notation): C₂₄H₂₉NaO₈
• CAS Number: 15087-01-1
• Molecular Weight: 468.47
• Beilstein/REAXYS Number: 6043458
• MDL number: MFCD00271561
• UNSPSC Code: 51111800
• PubChem Substance ID: 24894430
• NACRES: NA.77

Properties

• sterility: non-sterile
• Quality Level: 200
• assay: ≥99% (HPLC)
• form: powder
• technique(s): ELISA: suitable
• solubility: water: 20 mg/mL, clear, colorless
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: [Na+].[H][C@]12CC[C@]3(C)C(=O)CC[C@@]3([H])[C@]1([H])CCc4cc(O[C@@H]5O[C@@H]([C@@H](O)[C@H](O)[C@H]5O)C([O-])=O)ccc24
• InChI: 1S/C24H30O8.Na/c1-24-9-8-14-13-5-3-12(10-11(13)2-4-15(14)16(24)6-7-17(24)25)31-23-20(28)18(26)19(27)21(32-23)22(29)30;/h3,5,10,14-16,18-21,23,26-28H,2,4,6-9H2,1H3,(H,29,30);/q;+1/p-1/t14-,15-,16+,18+,19+,20-,21+,23-,24+;/m1./s1
• InChI key: PBULYLQKWDXDFZ-QHIGSJCSSA-M

Description

Application

Estrone 3-(β-D-glucuronide) sodium salt has been used as a standard:

• to estimate estrone conjugate (E1Cs) from urine samples by enzyme immunoassays (EIAs)
• to determine corticosterone metabolites from fecal and water samples by EIA
• to estimate progesterone and estrogen levels in feces of Chinese goral by EIA

Biochem/physiol Actions

Estrone 3 glucuronide (E3G) is a urinary metabolite of estrogen. Higher levels of estrone 3 glucuronide are observed during the early onset of the fertile period of the menstrual cycle.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)