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K3628

Sigma-Aldrich

Kininogen, low molecular weight from human plasma

≥95% (SDS-PAGE), lyophilized powder

Synonym(s):

LMW kininogen

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About This Item

MDL number:
MFCD00131428
UNSPSC Code:
12352200
NACRES:
NA.32
Pricing and availability is not currently available.

biological source

human plasma

Quality Level

200

assay

≥95% (SDS-PAGE)

form

lyophilized powder

mol wt

64000 Da

UniProt accession no.

P01042

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... KNG1 (includes EG:3827)

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biological source

mouse

biological source

mouse

biological source

rabbit

biological source

mouse

clone

N29, monoclonal

clone

B3B11, monoclonal

clone

polyclonal

clone

21C8, monoclonal

species reactivity

human

species reactivity

human

species reactivity

human, rat, pig, mouse

species reactivity

human

Gene Information

human ... ITGB1(3688)

Gene Information

human ... ITGB1(3688)

Gene Information

human ... ITGB1(3688)

Gene Information

human ... ITGB1(3688)

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

UniProt accession no.

P55268

UniProt accession no.

P55268

UniProt accession no.

P05556

UniProt accession no.

P55268

Application

Kininogen, low molecular weight from human plasma has been used to study rMASP-1 (recombinant mannose-binding lectin-associated serine protease 1)-mediated cleavage of LK (low molecular weight kininogen).[1] It has been used as a standard for protein identification in milk-proteomics study.[2]

Biochem/physiol Actions

Extracellular cysteine proteinase inhibitor.
LMW kininogen is a major extracellular cysteine proteinase inhibitor. Tissue kallikrein releases bradykinin, a potent bronchoconstrictor and vasoactive agent, from both HMW and LMY kininogen.

Physical form

Lyophilized from a solution in sodium acetate and sodium chloride.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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    Certificates of Analysis (COA)

    Lot/Batch Number
    SLCK4817
    SLCF0493
    SLCB8675
    SLCB3444
    SLCB1045

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