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P5669

Sigma-Aldrich

Pyridoxine

≥98%

Synonym(s):

Pyridoxol, Vitamin B6

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About This Item

Empirical Formula (Hill Notation):
C8H11NO3
CAS Number:
65-23-6
Molecular Weight:
169.18
EC Number:
200-603-0
MDL number:
MFCD00006335
UNSPSC Code:
12352104
PubChem Substance ID:
24898690
NACRES:
NA.28
Pricing and availability is not currently available.

Quality Level

100

assay

≥98%

form

powder

technique(s)

HPLC: suitable

color

white to off-white

mp

159-162 °C (lit.)

SMILES string

Cc1ncc(CO)c(CO)c1O

InChI

1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3

InChI key

LXNHXLLTXMVWPM-UHFFFAOYSA-N

Gene Information

human ... CYP1A2(1544)

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General description

Pyridoxine (vitamin B6) is a form of vitamin B6. Other forms include the aldehyde pyridoxal and the amide pyridoxamine. It is an important cofactor for metabolism.[1]
Vitamin B group are water-soluble and exists in six forms which includes the pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phospate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate.[2] Vitamin B6 is distributed in nuts, whole grains and animal meat.[3]

Application

Pyridoxine has been used as a component of:
  • artificial diet for sugarcane aphid pest[4]
  • modified Strullu and Romand (MSR) medium for carrot root organ culture[5]
  • Luria broth for E coli cultures[6]

Pyridoxine is used in cell culture and other applications as a precursor to pyridoxal phosphate. It has been used as a standard in RP-HPLC (reversed phase high performance liquid chromatography) method. Pyridoxine has been used as a diet supplement to study lipid profile in rats.[7]

Biochem/physiol Actions

Pyridoxine plays a key role in cell maintenance and amino acid metabolism.[2] Deficiency of vitamin B6 leads to anemia especially in pregnant women[8] and seizures in newborns.[3] It serves as cofactor for heme biosynthesis during δ-amino levulinic acid formation[8], γ-aminobutyric acid (GABA) transaminase and glutamic acid decarboxylase.[9] Vitamin B6 also helps in reactive oxygen species (ROS) scavenging and helps plants in overcoming the abiotic and biotic stress.[10]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    STBJ8734
    STBH9301
    STBH1389
    STBF3208V
    STBG4285V

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