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SAB4300270

Sigma-Aldrich

Anti-phospho-AURKA (pThr288) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-AIK antibody produced in rabbit, Anti-ARK1 antibody produced in rabbit, Anti-AURA antibody produced in rabbit, Anti-AURORA2 antibody produced in rabbit, Anti-aurora kinase A antibody produced in rabbit

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41
Pricing and availability is not currently available.
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~48 kDa

species reactivity

mouse, human

concentration

1 mg/mL

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This Item
19511A566069244
assay

≥95.0% (HPLC)

assay

≥95.0% (HPLC)

assay

≥75%

assay

≥95.0% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

300

Quality Level

100

form

liquid

form

liquid

form

lyophilized powder

form

liquid

pH

7.0-8.0

pH

7.0-8.0

pH

-

pH

7.0-8.0

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

storage temp.

−20°C

Immunogen

Peptide sequence around phosphorylation site of threonine 288 (R-T-T(p)-L-M), according to the protein AURKA.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Target description

Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control. Phosphorylates numerous target proteins, including ARHGEF2, BRCA1, KIF2A, NDEL1, PARD3, PLK1 and BORA. Regulates KIF2A tubulin depolymerase activity By similarity. Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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