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Key Documents

SAB4300529

Sigma-Aldrich

Anti-α-Synuclein (SNCA) Antibody

rabbit polyclonal

Synonym(s):

Anti-NACP antibody produced in rabbit, Anti-alphaSYN antibody produced in rabbit, Anti-synuclein, alpha antibody produced in rabbit

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About This Item

MDL number:
MFCD02095740
UNSPSC Code:
12352203
NACRES:
NA.41

Product Name

Anti-Snca (Ab-136) antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~18 kDa

species reactivity

mouse, human, rat

Immunogen

Peptide sequence around aa. 134-138 (Q-D-Y-E-P), according to the protein Snca.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Target description

May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
951421278

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