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SAB4300609

Sigma-Aldrich

Anti-FLT4 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-FLT41 antibody produced in rabbit, Anti-LMPH1A antibody produced in rabbit, Anti-PCL antibody produced in rabbit, Anti-VEGFR3 antibody produced in rabbit, Anti-fms-related tyrosine kinase 4 antibody produced in rabbit

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

Pricing and availability is not currently available.

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~160 kDa

species reactivity

human

concentration

1 mg/mL

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This Item
95068R0514R0250
form

solid

form

-

form

powder

form

powder

storage temp.

15-25°C

storage temp.

-

storage temp.

-

storage temp.

room temp

mp

80 °C

mp

-

mp

-

mp

-

pH

5.5-7.0 (25 °C, 100 g/L in H2O)

pH

-

pH

-

pH

-

density

1.465 g/cm3 at 20 °C

density

-

density

-

density

-

General description

Fms related tyrosine kinase 4 (FLT4) is also known as vascular endothelial growth factor receptor 3 (VEGFR3). It is expressed in the blood and lymphatic endothelial cells during early development. The gene encoding FLT4 is localized on human chromosome 5q35.3.

Immunogen

Peptide sequence around aa. 1279-1283 (L-A-S-E-E), according to the protein FLT4.

Application

Anti-FLT4 antibody produced in rabbit has been used in immunohistochemistry.

Biochem/physiol Actions

Fms related tyrosine kinase 4 (FLT4) has a role in lymphangiogenesis and angiogenesis. It acts as an activator in signaling pathways. Mutations in the gene encoding FLT4 have been linked to Milroy disease.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Target description

Receptor for VEGFC. Has a tyrosine-protein kinase activity.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Rapid quantitation of avenanthramides in oat-containing products by high-performance liquid chromatography coupled with triple quadrupole mass spectrometry (HPLC-TQMS).
Xie Z, et al.
Food Chemistry, 224(9-10), 280-288 (2017)
Maria Guadalupe Quiroz Vazquez et al.
Biophysical chemistry, 263, 106391-106391 (2020-05-16)
The misfolding of protein and its assembly into amyloid fibrils with a characteristic β-sheet-rich secondary structure, cause a lot of illnesses. Polyphenols have been extensively studied as a class of amyloid inhibitors, whose effect depends on the position and number
Mass spectrometric characterisation of avenanthramides and enhancing their production by germination of oat (Avena sativa).
de Bruijn WJC, et al.
Food Chemistry, 63(9-10), 419-423 (2018)
Selective and sensitive LC-MS determination of avenanthramides in oats.
Jastrebova J, et al.
Chromatographia, 63(9-10), 419-423 (2006)
Oswaldo Hernandez-Hernandez et al.
Food chemistry, 343, 128408-128408 (2020-11-08)
From a mutagenized oat population, produced by ethyl methanesulfonate mutagenesis, hulled grains from 17 lines with elevated avenanthramide (AVN) content were selected and their AVN structures, concentrations and antioxidant potentials were determined by HPLC-MS2 and HPLC equipped with an on-line

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