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SAB5700622

Sigma-Aldrich

Anti-PCNA antibody produced in rabbit

Synonym(s):

ATLD2, PCNA

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

Pricing and availability is not currently available.

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

28

species reactivity

mouse, human, rat

concentration

2.62 mg/ml

technique(s)

immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

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1 of 4

This Item
SAB1412471SAB1412666SAB1412667
Gene Information

human ... RUNX1(861)

Gene Information

human ... RUNX1(861)

Gene Information

human ... RUNX2(860)

Gene Information

human ... RUNX2(860)

clone

3A8, monoclonal

clone

3A1, monoclonal

clone

1D2, monoclonal

clone

3F5, monoclonal

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

General description

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human PCNA (NP_002583.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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    Regioselective synthesis and biological evaluation of novel bis (2-chloroquinolines).
    Rajesh K, et al.
    Research on Chemical Intermediates, 39(9), 4259-4267 (2013)
    Keith Jones et al.
    Organic & biomolecular chemistry, 1(24), 4380-4383 (2003-12-20)
    The synthesis of the quinoline alkaloid atanine 6, by selective demethylation of the 2,4-dimethoxyquinoline 11 is presented. An alternative demethylation utilising a thiolate anion leads to the regioisomeric 4-hydroxyquinoline 13.
    Ultrasound-promoted synthesis of novel 2-chloroquinolin-4-pyrimidine carboxylate derivatives as potential antibacterial agents.
    Balaji GL, et al.
    Research on Chemical Intermediates, 39(4), 1807-1815 (2013)
    Quinoline alkaloids. Part XIII. A convenient synthesis of furoquinoline alkaloids of the dictamnine type.
    Collins JF, et al.
    Journal of the Chemical Society. Perkin Transactions 1, 94-97 (1973)

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