Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

SML3348

Sigma-Aldrich

JWH-018

≥98% (HPLC)

Synonym(s):

1-Naphthalenyl(1-pentyl-1H-indol-3-yl)methanone, 3-(1-Naphthoyl)-1-pentylindole, AM 678, JWH 018

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C24H23NO
CAS Number:
Molecular Weight:
341.45
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

Pricing and availability is not currently available.

Quality Level

assay

≥98% (HPLC)

form

powder

drug control

USDEA Schedule I

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(C1=CN(CCCCC)C2=C1C=CC=C2)C3=CC=CC4=C3C=CC=C4

InChI

1S/C24H23NO/c1-2-3-8-16-25-17-22(20-13-6-7-15-23(20)25)24(26)21-14-9-11-18-10-4-5-12-19(18)21/h4-7,9-15,17H,2-3,8,16H2,1H3

InChI key

JDNLPKCAXICMBW-UHFFFAOYSA-N

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
CLS11415CLS11405CLS11495
material

flat bottom flask, polypropylene cap, polycarbonate

material

flat bottom flask, polycarbonate , polypropylene cap

material

flat bottom flask, polycarbonate , polypropylene cap

material

flat bottom flask, polycarbonate , polypropylene cap

sterility

sterile

sterility

sterile

sterility

sterile

sterility

sterile

manufacturer/tradename

Corning 11425

manufacturer/tradename

Corning 11415

manufacturer/tradename

Corning 11405

manufacturer/tradename

Corning 11495

capacity

500 mL

capacity

250 mL

capacity

125 mL

capacity

3 L

feature

cap: no, C-Flex tubing

feature

cap: no, C-Flex tubing

feature

cap: no, C-Flex tubing

feature

cap: no, C-Flex tubing

packaging

case of 2

packaging

case of 4

packaging

case of 6

packaging

case of 2

Biochem/physiol Actions

JWH-018, a synthetic cannabinoid, is a potent and selective full agonist at the CB1 and CB2 cannabinoid receptors. JWH-018 mimic the effects of Δ9-tetrahydrocannabinol (THC) and is found in several versions of the herbal mixture “Spice.”
Potent and selective full agonist at the CB1 and CB2 cannabinoid receptors

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

STOT SE 3

target_organs

Central nervous system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


  • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number

    It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

    If you need assistance, please contact Customer Support

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist
    Brady K Atwood
    British Journal of Pharmacology, 160, 585-593 (2010)
    Synthetic cannabinoids JWH-018, JWH-122, UR-144 and the phytocannabinoid THC activate apoptosis in placental cells
    Marta Almada, Patricia Alves, Bruno M Fonseca, Cristina Amaral , Natercia A Teixeira
    Toxicology Letters, 319, 129-137 (2020)

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service