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SRP0594

Sigma-Aldrich

Mouse TDO2, His-Tag

recombinant, expressed in E. coli

Synonym(s):

3-dioxygenase-2, TDO, Tryptophan 2

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.26
Pricing and availability is not currently available.

recombinant

expressed in E. coli

form

frozen liquid

mol wt

49 kDa

UniProt accession no.

P48776

shipped in

dry ice

storage temp.

−70°C

Gene Information

mouse ... TDO2(56720)

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Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

rabbit

biological source

mouse

biological source

rabbit

biological source

mouse

antibody form

IgG fraction of antiserum

antibody form

purified immunoglobulin

antibody form

IgG fraction of antiserum

antibody form

purified immunoglobulin

UniProt accession no.

Q96GD4

UniProt accession no.

O14965

UniProt accession no.

Q9UQB9

UniProt accession no.

Q96GD4

species reactivity

rat, mouse, human

species reactivity

human, mouse

species reactivity

human

species reactivity

human

General description

Mouse Tryptophan 2,3-dioxygenase-2 (TDO2), GenBank Accession No.NM_019911, a.a. 2-406(end) with an Nterminal His-tag, expressed in an E. coli cell expression system. MW = 49 kDa.

Physical form

Aqueous solution

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Thomas A Russo et al.
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Hypervirulent (hypermucoviscous) Klebsiella pneumoniae (hvKP) strains are an emerging variant of "classical" K. pneumoniae (cKP) that cause organ and life-threatening infection in healthy individuals. An understanding of hvKP-specific virulence mechanisms that enabled evolution from cKP is limited. Observations by our
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In order to survive inside macrophages, Salmonella produces a series of proteins encoded by genes within Salmonella pathogenicity island 2 (SPI-2). In the present study, we report that Fur, a central regulator of iron utilization, negatively controls the expression of
Hypoferremia of infection: a double-edged sword?
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Nature medicine, 20(4), 419-424 (2014-03-25)
In response to microbial infection, expression of the defensin-like peptide hepcidin (encoded by Hamp) is induced in hepatocytes to decrease iron release from macrophages. To elucidate the mechanism by which Salmonella enterica var. Typhimurium (S. typhimurium), an intramacrophage bacterium, alters
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