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SRP8048

Sigma-Aldrich

PEDF mouse

recombinant, expressed in CHO cells, FLAG® tagged, >95% (SDS-PAGE)

Synonym(s):

Caspin, PC cell-derived growth factor, Pigment epithelium-derived factor, Stromal cell-derived factor 3

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About This Item

CAS Number:
607410-75-3
UNSPSC Code:
12352202
NACRES:
NA.32
Pricing and availability is not currently available.

biological source

mouse

recombinant

expressed in CHO cells

tag

FLAG® tagged

assay

>95% (SDS-PAGE)

form

lyophilized

mol wt

~47 kDa by SDS-PAGE

packaging

pkg of 10 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

<0.01 EU/μg endotoxin, tested

color

white

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PEDF mouse recombinant, expressed in CHO cells, FLAG&#174; tagged, &gt;95% (SDS-PAGE)

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PDGF-BB from mouse recombinant, expressed in E. coli, &#8805;98% (SDS-PAGE), &#8805;98% (HPLC), suitable for cell culture

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PDGF-BB from mouse

PDGF-AA from mouse recombinant, expressed in E. coli, &#8805;98% (SDS-PAGE), &#8805;98% (HPLC), suitable for cell culture

SRP3228

PDGF-AA from mouse

biological source

mouse

biological source

human

biological source

mouse

biological source

mouse

assay

>95% (SDS-PAGE)

assay

≥95% (HPLC), ≥95% (SDS-PAGE)

assay

≥98% (HPLC), ≥98% (SDS-PAGE)

assay

≥98% (HPLC), ≥98% (SDS-PAGE)

recombinant

expressed in CHO cells

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

mol wt

~47 kDa by SDS-PAGE

mol wt

~44.5 kDa

mol wt

24.4 kDa

mol wt

28.7 kDa

form

lyophilized

form

lyophilized

form

lyophilized

form

lyophilized

impurities

<0.01 EU/μg endotoxin, tested

impurities

endotoxin, tested

impurities

<0.1 EU/μg endotoxin, tested

impurities

<0.1 EU/μg endotoxin, tested

General description

Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.

Physical form

Lyophilized from PBS.

Reconstitution

Reconstitute with 100 μL deionized water.

Other Notes

Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG®-tag.

Legal Information

FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    P22501211

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