U4125

Uridine 5′-(trihydrogen diphosphate) sodium salt from Saccharomyces cerevisiae

95-100%

• Synonym(s): UDP sodium salt, Uridine 5′-(trihydrogen pyrophosphate) sodium salt
• Empirical Formula (Hill Notation): C₉H₁₄N₂O₁₂P₂ · xNa⁺
• CAS Number: 21931-53-3
• Molecular Weight: 404.16 (free acid basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278767
• NACRES: NA.77

Properties

• Quality Level: 200
• Assay: 95-100%
• solubility: H₂O: soluble 100 mg/mL, clear, colorless to very faintly yellow
• storage temp.: −20°C
• SMILES string: [Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])([O-])=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H14N2O12P2.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3
• InChI key: GFASEGWJDXDCKZ-UHFFFAOYSA-K
• Gene Information: human ... LPAR4(2846), LTB4R(1241), P2RY1(5028), P2RY10(27334), P2RY11(5032), P2RY12(64805), P2RY13(53829), P2RY14(9934), P2RY2(5029), P2RY4(5030), P2RY5(10161), P2RY6(5031), P2RY8(286530)

Description

Application

UDP has been used as a purinergic agonist to study its effects on absorptive cationic flux in cochlear outer sulcus cells (OSC) and vestibular transitional cells (VTC). UDP has also been used for nucleoside diphosphatase (NDPase) activity assays in rabbit retinae.

Biochem/physiol Actions

P2Y receptor agonist.

Features and Benefits

This compound is featured on the P2 Receptors: P2Y G-Protein Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Preparation Note

Uridine 5′-(trihydrogen diphosphate) sodium or UDP sodium salt is soluble in water at 100 mg/ml and yields a clear, colorless to very faint yellow solution.

Safety Information

• Pictograms: GHS08
• Signal Word: Warning
• Hazard Statements: H371
• Precautionary Statements: P260 - P264 - P270 - P308 + P311 - P405 - P501
• Hazard Classifications: STOT SE 2
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable